Based on 120 reviews

Your Second Act Starts Now

Personalized hormone replacement therapy that puts you back in the driver’s seat—energy, clarity, confidence.

Goodbye Midnight Heat Waves
Hello Lifted Libido & Mood
Confidence From the Inside Out
Start My 2-Minute Quiz

Say Goodbye to

hot flashes
mood swings
sleepless nights
brain fog
low libido
weight gain
"The hot flashes are gone, I’m sleeping again, and I feel like I have me back."
Estradiol tablets
– Emily R.
Verified Patient
"I was skeptical, but within a few weeks,
I noticed real changes. Thank you!"
Passion cream
– Maria T.
Verified Patient
"From the quiz to receiving my treatment, I felt supported and understood."
Estradiol gel
– Kathy B.
Verified Patient

Choose Your Personalized Path

Estradiol Gel

A fast-absorbing topical gel that provides steady, effective estrogen support to reduce:

Hot flashes & night sweats
Mood swings & irritability
Skin changes
Vaginal dryness
Estradiol Tablets

Oral estrogen therapy that fits easily into your routine.Perfect for women looking for consistent, full-body symptom relief.

Stabilized mood
Improved energy & clarity
Relief from hot flashes & brain fog
Support for bone and heart health
Progesterone Tablets

Taken alongside estrogen to balance your hormone levels and protect your health.

Promotes better sleep
Reduces anxiety & emotional swings
Supports uterine health
Helps prevent estrogen-related side effects
Estradiol Patch

Taken alongside estrogen to balance your hormone levels and protect your health.

Promotes better sleep
Reduces anxiety & emotional swings
Supports uterine health
Helps prevent estrogen-related side effects

What is Hormone Therapy?

Hormone Replacement Therapy (HRT) is a safe and effective way to restore declining hormone levels, especially estrogen and progesterone, to relieve symptoms of perimenopause and menopause.

We use bioidentical hormones—compounds that mimic the hormones your body naturally produces—to provide targeted, personalized relief.

Why Choose Piper?

Clinically-guided care
Our medical team reviews your symptoms and history to create
a plan made just for you.
Bioidentical hormones
Safe, effective formulations designed
to mimic your natural hormones.
Convenient delivery
Medications delivered
directly to your door.
Ongoing support
We're here for you
every step of the way.
Ready to feel unstoppable?

You might be in perimenopause or
menopause if you’re experiencing:

Changes in your period
Trouble sleeping
Loss of libido
Weight gain (especially around the belly)
Forgetfulness or brain fog
Vaginal dryness or discomfort
Mood swings, depression, or anxiety

Real Relief. Real Results.

"I felt like my body was falling apart. Piper made it make sense — and made it easy. My doctor helped me start estradiol gel and had it shipped straight to me. Within weeks, I felt like me again."

Estradiol tablets
– Rachel
Verified Patient

"I was terrified to start HRT, but Piper actually listened. My doctor got what I was going through and tailored my treatment with care. The Passion Cream and progesterone helped calm the rage, lift my mood, and I finally started sleeping again."

Passion cream
– Linda
Verified Patient

"Everything felt personal with Piper — no waiting rooms, no generic plans. My care was truly mine. The regular check-ins ease my mind, and I feel seen. Plus, the meds? Gorgeous. I look forward to using them."

Estradiol gel
– Anna
Verified Patient

"I didn’t realize how much I had normalized feeling awful until Piper stepped in. My hot flashes, night sweats, and constant anxiety were out of control. The estradiol gel made a difference fast — and the whole process felt so easy and respectful."

Estradiol tablets
– Denise
Verified Patient

"Starting HRT felt like a big decision, but Piper made it feel empowering. I finally got answers, a plan that made sense, and support every step of the way. The combination of progesterone and estradiol helped balance my mood and bring me back to center."

Passion cream
– Carla
Verified Patient

"From the first quiz to receiving my treatment, I felt supported and understood. Piper helped me feel like my symptoms weren’t ‘just in my head.’ My skin, sleep, and mood have all improved — I only wish I’d started sooner."

Estradiol gel
– Vanessa
Verified Patient

Ready to feel like yourself again?

It starts with a simple online assessment.
Tell us about your symptoms— we’ll recommend the best treatment plan
for your body and your goals.
Take the Assessment

FAQs

Is Hormone Replacement Therapy (HRT) safe?

Yes, HRT is safe for most healthy women when prescribed by a licensed doctor. Piper’s physicians evaluate each patient individually to ensure treatments are appropriate and tailored to your unique needs.

Do I need blood tests to get started?

No — Piper doctors treat based on symptoms, not lab results. Hormone levels can fluctuate daily, so symptom-based care is often more accurate and effective for menopause treatment.

How soon will I feel better on HRT?

Many women notice symptom relief within the first few weeks, especially with hot flashes, sleep disturbances, or mood shifts. Full benefits often become more noticeable within about three months.

Can I pause or cancel my treatment?

Absolutely. Piper gives you full control — you can pause your subscription for up to 90 days or cancel anytime without pressure or penalties.

What products does Piper offer?

Piper offers FDA-approved treatments including oral estradiol and progesterone tablets, topical estradiol gel, and Passion Cream for vaginal or libido support — all designed to meet different needs and preferences.

Is Piper available for women in perimenopause?

Yes. Piper supports women in both menopause and perimenopause. If you’re starting to notice symptoms like irregular periods, hot flashes, or mood changes, our doctors can help you find the right treatment to feel better sooner.

What makes Piper different from other menopause care options?

Piper offers care that’s built around you — with real doctors who listen, FDA-approved treatments tailored to your body, and the comfort of receiving care and medication right from home. There’s no guesswork, no waiting rooms, and no hidden fees.

What if I have questions during treatment?

You’ll have ongoing access to your Piper doctor and care team. You can message your provider anytime through your patient portal — whether you need adjustments or just reassurance.

Will my medications come discreetly packaged?

Yes. All Piper medications are shipped in discreet packaging, so your privacy is always protected.

You don’t have to
Push through menopause.

There’s a better way. Personalized hormone therapy is here—and it works.
Let’s get you feeling like yourself again.
Start My JOURNEY
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